C-reactive protein in patients with coexistent periodontal disease and acute coronary syndromes
: Maciej R. Czerniuk
: journal of clinical periodontology
Aim: To evaluate periodontal disease (PD) influence on changes in high-sensitivity
C-reactive protein (hsCRP) concentrations in patients with acute coronary syndromes
and coexistent PD.
Materials and Methods: Dental examinations were carried out in a group of 50
consecutive patients, less than 60 years old, hospitalized as a result of acute coronary
syndromes. The patients were divided into two groups on the basis of own-constructed
combined PD score (group 2: more advanced; and group 1: less advanced PD) as well
as clinical attachment loss (CAL) Ã¢â‚¬â€œ group 4: CAL 43 mm; group 3: CAL 43 mm.
Blood samples for hsCRP estimation were taken at admission, after 10/12 days and
long term after acute coronary syndromes.
Results: A statistically significant decrease in hsCRP was observed among three
consecutive blood sample examinations in groups 2 and 4, whereas it was only seen
between examination 1 and examination 2 in groups 1 and 3.
Conclusions: Although no statistically significant difference of hsCRP was found
between studied groups, patients with less advanced PD, either estimated with the use
of own-constructed combined score or on the basis of CAL, have significantly longer
diminution of inflammatory response monitored with hsCRP concentrations.
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