Autogenous bone graft in conjunction with enamel matrix derivative in the treatment of deep periodontal intra-osseous defects: a report of 13 consecutively treated patients
: Leonardo Trombelli
: Blackwell Synergy
Aim: The purpose of the present study was to investigate the effectiveness of a
regenerative procedure based on supra-crestal soft tissue preservation in association
with combined autogenous bone (AB) graft/enamel matrix derivative (EMD)
application in the treatment of deep periodontal intra-osseous defects.
Methods: Thirteen consecutively treated patients, seven females and six males, aged
30Ã¢â‚¬â€œ65 years, three smokers, were included. A total of 15 deep, one- to two-wall intraosseous
defects were selected. Immediately before surgery and 6 months after surgery,
pocket probing depth (PPD), clinical attachment level (CAL), and gingival recession
(REC) were recorded.
Results: PPD amounted to 9.4 1.8mm before surgery, and decreased to
4.7 1.2mm post-surgery (po0.0000). CAL varied from 10.5 2.0mm pre-surgery
to 6.2 1.7mm post-surgery (po0.0000), with CAL gain averaging 4.3 1.4 mm.
Fourteen (93.3%) defects presented CAL gain X3 mm. REC change was
0.4 0.7 mm.
Conclusions: Results from the present study indicated that a regenerative procedure
based on supra-crestal soft tissue preservation and combined AB/EMD treatment leads
to a clinically and statistically significant improvement of soft tissue conditions of deep
periodontal intra-osseous defects.
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