Diabetes mellitus promotes periodontal destruction in children
: Blackwell Synergy
Aim: The association between diabetes mellitus and periodontal attachment and
bone loss is well established. Most of the prior literature has focused on adults, and
studies in children have mostly reported gingival changes. Our aim was to assess
the periodontal status of a large cohort of children and adolescents with diabetes.
Material and Methods: We examined 350 children with diabetes (cases) and 350
non-diabetic controls (6Ã¢â‚¬â€œ18 years of age). Using three different case definitions for
periodontal disease, which incorporated gingival bleeding and/or attachment loss
findings, multiple logistic regression analyses adjusting for age, gender, ethnicity,
frequency of prior dental visits, dental plaque, and examiner were performed.
Results: Subjects with diabetes had increased gingival inflammation and attachment
loss compared with controls. Regression analyses revealed statistically significant
differences in periodontal destruction between cases and controls across all disease
definitions tested (odds ratios ranging from 1.84 to 3.72). The effect of diabetes on
periodontal destruction remained significant when we separately analysed 6Ã¢â‚¬â€œ11 and
12Ã¢â‚¬â€œ18 year old subgroups.
Conclusions: These findings demonstrate an association between diabetes and an
increased risk for periodontal destruction even very early in life, and suggest that
programmes to address periodontal needs should be the standard of care for diabetic
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