Oral health of monozygotic twins with and without coronary heart disease: a pilot study
: Blackwell Synergy
Aim: The purpose of this study was to investigate the oral health in monozygotic
twins where one twin had coronary heart disease (CHD) and the other twin had no
clinical signs of the disease.
Methods: Ten monozygotic twin pairs (age 55Ã¢â‚¬â€œ81 years, eight male, and two female
pairs) were recruited from the Swedish twin register. The inclusion criterion for
participation was discordance regarding the presence of CHD within every twin pair.
All participants underwent a full dental clinical examination including a panoramic
Results: Twins with CHD had 51.5% bleeding on probing compared with 21.1%
without CHD (p50.01), and more pathological pockets (X4 mm) were detected
among those with CHD (20 15 versus 8 5), p50.047). Twins with CHD had a
reduced horizontal bone level in comparison with the healthy group (73% versus 78%,
p50.03). Logistic analyses using odds ratio (OR) showed that an increase of one
periodontal pocket (X4 mm) resulted in an increased risk for the actual twin of
belonging to the CHD group (OR 1.17, p50.03).
Conclusions: This study indicates worsened periodontal conditions among twins with
CHD compared with their siblings with no history of CHD. This strengthens the
association between periodontal inflammation and the presence of atherosclerosis.
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