Use of platelet gel with connective tissue grafts for root coverage: a randomized-controlled trial
: Huseyin Gencay Keceli
: Blackwell Synergy
Background: Platelet-rich plasma (PRP) was speculated to be a promoter of
periodontal regeneration. There are only a few clinical comparative studies using
PRP in the treatment of gingival recession.
Aim: The aim of the present study was to compare connective tissue graft
(CTG)1PRP with CTG alone in the treatment of gingival recession.
Material and Methods: Forty patients with Miller I/II recessions were included.
Each recession was randomly treated with either CTG1PRP or CTG. Clinical
variables were recorded at baseline and at 6 weeks, 6 and 12 months. Root coverage
(RC) and attachment gain (AG) were also calculated.
Results: Probing depth, recession depth, clinical attachment level, keratinized tissue
width and recession width (RW) were improved in both study groups. However, no
difference was observed between groups, except RW. RW in the control group was
statistically lower than the test group at all follow-up periods.
Conclusion: Treatment of recession with CTG or a CTGÃ¢â‚¬â€œPRP combination resulted
in favourable clinical outcomes. However, no difference could be found between CTG
and CTG1PRP. Whether much longer follow-up studies with higher statistical power
may change these results remains questionable.
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